Practice and Treatment Guidelines

Most Recent

• CDC Obstetrical Tip Sheet - Hepatitis B Screening, Testing, and Management of Pregnant Persons

• Kentucky Hepatitis Academic Mentorship Program (KHAMP) - Tele-mentoring training program for primary care providers.

• University of New Mexico Hepatitis C ECHO - Each month Project ECHO offers a two-hour virtual hepatitis C virus (HCV) training for New Mexico and/or Indian Country clinicians and their teams.

• University of Utah Hepatitis C ECHO - Every Friday 11:30-1:00 PM Mountain Time.

• CDC Recommendations for Hepatitis C Testing Among Perinatally Exposed Infants and Children - In November 2023, the CDC updated testing guidance for infants and children perinatally exposed to Hep C.

• Hepatitis C Direct-Acting Antiviral (DAA) Therapy Primary Care Provider Attestation - Form to waive prior authorizations for Hep C medications from Hawaiʻi MedQUEST insurance plans

• HBV Care in Key Communities: Minimizing Barriers and Optimizing Care - CME/CE-certified videos and podcasts on optimizing care for Asian American patients and special populations.

• Implementing Hepatitis B Universal Adult Screening and Vaccination: Clinical Answers for Healthcare Professionals - A 3-page PDF summarizing the updated CDC recommendations for hepatitis screening and vaccination.

• Hepatitis B Vaccination and Screening of Adults: Simple Steps to Protect Yourself from Serious Liver Disease - A 1-page PDF summarizing the updated CDC recommendations for hepatitis screening and vaccination.

• Updated Operational Guidance for Implementing CDC’s Recommendations on Testing for Hepatitis C Virus Infection - In July 2023, the CDC issued guidance for supporting automatic HCV RNA testing on all HCV antibody reactive samples.

• “Driving Hepatitis B Management: Universal Screening and Vaccination in Primary Care”(medscape.org) - This free, video-based activity is designed to support clinicians who are working to integrate updated CDC guidelines for hepatitis B virus (HBV) screening, testing, and vaccination into daily practice and is valid for credit through 6/12/2024.

• New CDC Hepatitis B Screening Recommendations for All Adults - In March 2023, the CDC released new recommendations for a 3-panel hepatitis B screening for all adults, regardless of risk.

• Hep Free Hawaiʻi Template Handout on Hep C Treatment for Patients - Mahalo to Dr. Paul Berg and the team and Wahiawa Health Center for requesting and inspiring this handout for patients. Please download and adapt for your own practice!

• Hawaiʻi Best Practice Reminder - Automatic Reflex Hepatitis C Virus (HCV) Antibody to RNA Reflex Testing - This handout was developed in 2022 by Hep Free Hawaiʻi and the Hawaiʻi Department of Health (in consultation with local laboratories and the CDC) to promote automatic hep C reflex testing to RNA from antibody. It includes guidance, billing and lab codes, and references.

• Mothers and babies can’t wait: A call for action to end mother-to-child transmission of hepatitis B - This white paper from the World Hepatitis Alliance outlines the context and human impact of mother-to-child transmission. It makes recommendations, which, when carried out in addition to established guidelines, will ensure that services are equitable, accessible, and available to all who need them.

• Provider materials on children, adolescents, young adults and pregnant people living with hepatitis C - In collaboration with specialists in the field of pediatrics, liver disease during pregnancy, harm reduction, and infectious disease, Hepatitis C Mentor and Support Group is offering digital and print materials available for providers free of charge (requires registration).

• Treatment in Pregnancy for Hepatitis C (Tip-HepC) Registry - The purpose of this global registry is to record outcomes for pregnant people and their infants exposed to hepatitis C direct-acting antivirals during pregnancy. Findings from the registry will be used to advance HCV treatment decision-making by clinical providers and programs worldwide. There is no date restriction in completing this registry (please note this is NOT a surveillance registry).

• National Clinician Consultation Center - Provides a warmline and online case form for clinician-to-clinician advice on hepatitis C mono-infection and co-infection testing, management, and treatment. For phone consultation, call (844) 437-4636 Monday – Friday, 9 a.m. – 8 p.m. ET.

• Management of Infants Born to Women with Hepatitis B Virus Infection for Pediatricians - Provider Tip Sheet from the CDC

• Hawai’i Learning Group - Resource hub for Harm Reduction Hawai’i ECHO, including hepatitis B and C modules.

• Point-of-Care Toolkit for Hepatitis B Screening and Care - toolkit to gather up-to-date insights and practical resources to assess the HBV burden in your region, access expert tips for improving screening and referral pathways in your practice, and download simplified algorithms for HBV treatment and monitoring and liver cancer surveillance.

• Bigg Elimination Tribute Project - module-based training to build attendees’ capacity, confidence, and knowledge to integrate HCV screening, testing, linkage-to-care/cure, and support programs into existing infrastructures. 4 CEUs for social workers and counselors are available.

• HBV Primary Care Guidance – simplified algorithm for hepatitis B screening, management, and treatment in the primary care setting, developed by National Task Force on Hepatitis B

• Clinical Guidelines Program (New York) – clinical guidelines related to the prevention and treatment of HIV/AIDS, hepatitis C, and substance use designed for practical use by non-specialist care providers

Billing and Coding

• Viral Hepatitis Guide for Primary Care Providers Screening, Vaccination, and Billing – guidance for appropriate hepatitis screening and immunizations, including billing codes and CDC recommendations. Updated April 2022 by the California Department of Public Health.

• Guide to Hepatitis C Testing – guidelines for primary care providers, including latest recommendations, billing codes, and resources for educating patients. From the American Academy of HIV Medicine and American College of Physicians

Insurance Coverage

• Hepatitis C Direct-Acting Antiviral (DAA) Therapy Primary Care Provider Attestation - Form to waive prior authorizations for Hep C medications from Hawaiʻi MedQUEST insurance plans. To qualify, you must attest to taking any HCV education, such as the free CE training module from University of Washington.

• MedQUEST Memo - Updating Hepatitis C Treatment Access - In December 2022, the Hawaiʻi State Medicaid program (“MedQUEST”) sent out a memo to its providers and plans, which focuses on alignment with the AASLD/IDSA treatment guidance, specifically stating:

  “The goal of this HCV policy is to assure adherence to the best practice guidance, currently outlined by the AASLD-IDSA HCV Guidance. For treatment regimens following the AASLD- IDSA HCV Guidance, there will be no prior authorization” [emphasis added]

• Direct Acting Antiviral (DAA) Medications for Treatment of Chronic Hepatitis C Infection – reduced restrictions for Hawaii Medicaid (MedQUEST) Fee-for-Service and Quest Integrated Plans (December, 2018)

US Food and Drug Administration (FDA)

• ALERT! FDA Drug Safety Communication – rare occurrence of serious liver injury with use of certain hepatitis C medicines in some patients with advanced liver disease (August, 2019)

The American Association for the Study of Liver Diseases (AASLD)

• Recommendations for Testing, Managing, and Treating Hepatitis C

• Practice Guidelines, including Treatment of Chronic Hepatitis B

The Centers for Disease Control and Prevention (CDC)

• Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2020

• Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices (2018)

• Recommendations for Prevention and Control of Hepatitis C Virus (HCV) Infection and HCV-Related Chronic Disease

Federal Bureau of Prisons (FBOP)

• Evaluation and Management of Chronic Hepatitis C Virus (HCV) Infection (2018)

European Association for the Study of the Liver (EASL)

• EASL Recommendations on the Treatment of Hepatitis C (2018)

• Hepatitis B EASL Guidelines (2017)

World Health Organization (WHO)

• Guidelines on Viral Hepatitis

Continuing Education and Training

• American Journal of Nursing – CE credits for hepatitis screening and treatment updates

• Clinical Care Options - CME/CE-certified interactive video module on diagnosis, treatment, and cure of HCV infection among persons who inject drugs

• ID Care Live – free online CME courses for healthcare professionals on hepatitis

• International Antiviral Society USA – free online CME/CE courses for healthcare professionals on hepatitis

• International Coalition of Hepatology Education Providers – free education and updates on hepatitis C for healthcare providers

• Optimizing Global Screening and Treatment Efforts to Mitigate Hep B Morbidity and Mortality - Tune in to this video as global hepatitis experts exchange ideas about ways to accelerate HBV elimination across different regions by optimizing patient outreach, testing, prevention, antiviral treatment, and monitoring. CME/CE are no longer available.

• University of Washington Online Hep B Course - free online modules with CME/CNE credits available

• University of Washington Online Hep C Course - free online modules with CME/CNE credits available

Other Resources

• HealthHCV - medical and consumer education and training programs to improve the ability of organizations, professionals, and individuals to address the needs of people living with viral hepatitis.

• HCV.com Provider Resources - hepatitis C quick reference guides, and other materials

• HBV Primary Care Guidance – simplified algorithm for hepatitis B screening, management, and treatment in the primary care setting, developed by National Task Force on Hepatitis B

• Hepatitis B Online: Challenges and Controversies - Expert Opinions for Challenging and Controversial Cases, with opinions submitted by experts from across the nation.

• Prime Hepatitis B Care and Treatment Toolkit - for patients and medical professionals

• Health Education for Liver Providers (H.E.L.P) - team-based training from National Hep B Task Force

• Clinician Consultation Center – free warm line for HCV management at (844) 437-4636 from 6 am - 2pm HST

• Hep Drug Interactions – resources to determine hep drug interactions for treating clinicians

• Addressing Viral Hepatitis in People with Substance Use Disorders – quick guide for clinicians and administrators from the United States Substance Abuse and Mental Health Service Administration (SAMHSA)

• Queens Liver Center - info includes electronic referral forms